Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process
نویسندگان
چکیده
منابع مشابه
Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process.
In this review, 2 cytokines are discussed with respect to the inflammatory processes that are fundamental to aging and mortality. Both interleukin (IL)-1 and IL-18 are members of the same structural family (IL-1 family, or IL-F); there are presently 9 members of this family, but with the exception of IL-1alpha, IL-1beta, and IL-18, the others are antagonists or remain without known function. IL...
متن کاملThe Value of Interleukin-8 and Interleukin-6 in Cervical Secretions as Predictors of Preterm Delivery
Background and Objective: Preterm birth occurs in 8% to 11% of all pregnancies and is responsible for 75% to 80% of all neonatal deaths. Cytokines may be involved in the etiology of preterm birth through their stimulation of prostaglandin synthesis. Cytokines may be released intocervicovaginal fluid during the breakdown of the chorio-decidual adhesion or from an inflammatory reactio...
متن کاملCytokines, interleukin-18, and the genetic determinants of vascular inflammation.
Inflammation and Vascular Disease In the past decade, atherogenesis has become recognized as an active, inflammatory vascular process rather than simply the result of passive endothelial injury with subsequent lipid infiltration.1 Evidence of inflammation is found locally in the vascular wall and systemically in the circulation. Participants in the inflammatory process within atherosclerotic pl...
متن کاملInterleukin 1-β, Interleukin-1 Receptor Antagonist, and Interleukin 18 in Children with Acute Spontaneous Urticaria
UNLABELLED Very little is known about the role of interleukin-1β (IL-1β) and interleukin-18 (IL-18) in urticaria. MATERIAL AND METHODS Serum levels of IL-1β, IL-1 receptor antagonist (IL-1RA), and IL-18 were measured in 56 children with urticaria and in 41 healthy subjects. RESULTS Serum IL-1β did not differ between children with acute urticaria and controls. Children with single episode of...
متن کاملOcular inflammation stimulated by intravitreal interleukin-8 and interleukin-1.
Interleukin-8 (IL-8), a cytokine with neutrophil chemotactic and activating properties, is known to be stimulated by IL-1. Fischer rats are more resistant to inflammation than Lewis rats probably due to a higher corticosteroid stress response. To determine the role of IL-8 in ocular inflammation, the effect of intravitreal injection of IL-8 was compared with that of IL-1 in both Lewis and Fisch...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 2006
ISSN: 0002-9165,1938-3207
DOI: 10.1093/ajcn/83.2.447s